Backed by science

Explore our selection of scientific studies on collagen, with key findings and takeaways to better understand its role in health and wellness.

Age-related decline in collagen production

Varani J. et al. “Decreased collagen production in chronologically aged skin”, Am J Pathol, 2006.

This study shows that type I collagen production in the dermis can decline by approximately 70% with age, contributing to the loss of skin density, thickness and firmness observed in older individuals.

Benefits of collagen peptide supplementation for skin health

Al-Atif H. “Collagen supplements for aging and wrinkles: A paradigm shift in the fields of dermatology and cosmetics”, Dermatol Pract Concept, 2022.

This review of clinical studies highlights that oral collagen peptide supplementation can improve skin hydration, elasticity and dermal collagen density, helping counteract some of the effects of age-related skin ageing.

Poor absorption and limited impact of dietary collagen, e.g. from meat consumption, unlike collagen peptides

Holwerda AM, van Loon LJC. “The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review”, Nutr Rev, 2022.

This review highlights that:

- Ingestion of non-collagen dietary proteins does not increase collagen synthesis in musculoskeletal connective tissues

- Native collagen, as found in meat products, is difficult to digest and poorly absorbed

- Gelatin is more easily digested, increasing blood levels of collagen-specific amino acids, but without demonstrating a direct stimulatory effect on collagen synthesis

- Collagen peptides show higher bioavailability, resulting in higher blood levels of these amino acids.

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