TrueColl^® One
Collagen Peptides

TrueColl® One is a patented B2B ingredient composed of true collagen peptides produced through precision fermentation using a food-grade yeast. It is specifically engineered to deliver only highly bioactive di- and tripeptides. Unlike conventional collagen peptides extracted from animal tissues, TrueColl® One is animal-free and effective at a very low daily dose to support active living, healthy ageing and longevity.

Conventional collagen peptides are obtained by hydrolyzing animal tissues and contain only small amounts of truly bioactive peptides. Produced through precision fermentation from a food-grade yeast, TrueColl®One is animal-free. It is specifically engineered to deliver only highly bioactive di- and tripeptides, enabling high efficacy and a very low daily dose.

Collagen is the major protein of animal connective tissues, not occurring naturally in plants. It has traditionally been obtained from animals, but its identity is defined by its molecular composition. Precision fermentation enables us to produce true collagen from a food-grade yeast without using animals and subsequently hydrolyze it into collagen peptides.

TrueColl® One is not plant-based, but it is animal-free and compatible with plant-based products. It is produced through precision fermentation using a food-grade yeast, which is a non-animal microorganism. Unlike plant-based collagen alternatives available on the market, TrueColl® One consists of true collagen peptides containing hydroxyproline, is highly bioactive and is effective at a very low dose.

Collagen is characterized by its high hydroxyproline content, an amino acid found in significant amounts only in collagen and closely associated with its biological properties. To improve bioavailability, collagen can be hydrolyzed into peptides. However, only certain peptides are truly bioactive, particularly di- and tripeptides containing hydroxyproline, such as GPO (glycine-proline-hydroxyproline), one of its most documented bioactive forms. Unlike conventional collagen peptides, which typically contain less than 1% GPO, TrueColl®One contains 50% GPO.

Thanks to deep-tech engineering, TrueColl® One contains only highly bioactive di- and tripeptides and is therefore effective at a very low dose of 100mg per day. In comparison, conventional collagen peptides extracted from animal tissues contain only small amounts of highly bioactive peptides and require daily doses of up to 20g.

Through dietary supplements and functional foods, TrueColl® One is designed to support health benefits related to beauty-from-within (skin health), mobility (joint health), active living and healthy ageing (longevity).

TrueColl® One is designed to deliver a superior collagen experience: strong real-world efficacy, easy and pleasant consumption, and no animal origin. Its high content of highly bioactive peptides makes it truly effective. Its high purity and tiny dose help minimize the taste, odor and side effects associated with high doses of conventional collagen peptides. It is natural, sustainable and compatible with plant-based lifestyles.

No. Thanks to its very low daily dose, high purity and new delivery formats, TrueColl® One eliminates the taste and odor constraints associated with high doses of conventional collagen peptides, delivering a superior consumer experience.

TrueColl® One removes major barriers for brands associated with conventional collagen peptides and opens new possibilities for innovation and value creation.
Its very low daily dose enables new delivery formats, from small capsules and tablets to gummies and new functional foods, and easy combinations with other active ingredients. Combined with unique efficacy and no animal origin, this enables brands to develop advanced, differentiated solutions and deliver a superior wellness experience to consumers.

Precision fermentation is a highly controlled production process based on the engineering and cultivation of microorganisms through fermentation, such as yeast, bacteria, fungi and microalgae, to produce animal-free specialty ingredients traditionally obtained through conventional processes, such as plant or animal extraction. The aim is to improve sustainability and deliver other specific benefits, including higher purity, bioavailability or bioactivity, an improved nutritional profile, lower manufacturing costs and a more reliable supply, or even to enable the development of entirely new ingredients.

No. TrueColl® One is not a genetically modified organism (GMO). It is produced through precision fermentation using a genetically engineered food-grade yeast as a production tool. During the purification process, the yeast is completely removed together with its genetic material.

TrueColl® One is still under development. A first proof of concept through in vitro testing has shown that a TrueColl® One prototype can deliver similar bioactivity at a 40-fold lower dose than commercial benchmarks, while also showing potential for even greater bioactivity. Several clinical studies are planned to confirm the efficacy of TrueColl® One in real-world conditions, characterize its specific health benefits and further investigate its mechanisms of action.

TrueColl® One is still under development. Although the collagen peptides it contains naturally occur in conventional collagen and have a well-established history of safe consumption, TrueColl® One is more concentrated and produced differently through precision fermentation. As part of our development roadmap, regulatory clearance will be obtained in each target market before commercialization, including GRAS status in the United States and Novel Food authorization in the European Union.

TrueColl® One is still under development. A pre-commercialization and sampling phase for partner brands is scheduled from early 2028, ahead of the full commercial launch. You can contact our team today to prepare for its integration into your upcoming new product developments.